The matchups for fall don't look very favorable, and a lot of games may be ugly. The few that I think are possible are:
EMU at Illinois
Ohio at Pitt
Indiana at Ball State
NIU at Vandy
Akron at Illinois
WMU at Michigan State
The MAC usually nabs about 3 wins against the P5. Last year the MAC got their usual three as Akron won at Northwestern, EMU won at Purdue, and Buffalo won at Rutgers. In 2017 the MAC managed four wins, when Ohio and CMU both won at Kansas, NIU won at Nebraska, and EMU won at Rutgers. 2019 may offset that, as there are no games against Kansas or Rutgers, who, between them, accounted for four of the seven wins over the P5 the last two years.
I'm thinking the MAC will be lucky to win 2 games against the P5 this year.
While we are at it, the MAC once in awhile manages to lose to an FCS team. If they can't beat many P5 teams this year, at least I hope they manage to win all their FCS games. The most risky of those look to be:
Kent St versus Kenn State (Kennesaw was very good last year)
NIU versus Illinois State (Illinois St is always good, and NIU has a new coach)
CMU versus Albany (Albany is good some years)
“We have two ears and one mouth so that we can listen twice as much as we speak.” ― Epictetus